Mercury Excretion and APO-E 4/3 4/4 Genotypes

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Recent research reveals that a genetic predisposition exists in some people that cause them not to excrete heavy metals efficiently.

The brain contains proteins that assist in the removal of waste products, including mercury. These proteins, called Apolipoprotein E (APO-E), reside in the cerebral spinal fluid surrounding the brain. They come in different types: APO-E2, APO-E3, and APO-E4. Each of these types has the ability to carry differing amounts of mercury out of the brain.

  • APO-E2 can transport 2 atoms of mercury out of the brain
  • APO-E3 can transport 1 atom of mercury out of the brain
  • APO-E4 can not transport mercury out of the brain

The genes we inherit from our parents determine which proteins our bodies have.

It naturally follows that those with APO-E4 / APO-E3 and those with APO-E4 / APO-E4 are poor excretors of mercury. These have the highest affinity for becoming ill from exposure to heavy metals.

Research has also shown that autistic children strongly-tend to have APO-E4 proteins. Research has also shown that people with APO-E4 / APO-E4 have an 80% chance of getting Alzheimer's disease.


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Disclaimer: We are not a doctors. We do not prescribe medication or practice medicine. No information we share is intended to prescribe medication or practice medicine, nor is it intended to prevent, treat or cure symptoms, conditions or diseases. We only express our opinions based on personal research and experience.

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